tert-butyl 4-phenylpiperidine-1-carboxylate

tert-butyl 4-phenylpiperidine-1-carboxylate - Names and Identifiers

Name	4-phenyl-1-Piperidinecarboxylic acid 1,1-dimethylethyl ester
Synonyms	tert-Butyl 4-phenylpiperidin-1-carboxylate tert-butyl 4-phenylpiperidine-1-carboxylate tert-Butyl (1R,4R)-4-phenylcyclohexylcarbamate 4-phenyl-1-Piperidinecarboxylic acid 1,1-dimethylethyl ester 1-Piperidinecarboxylic acid, 4-phenyl-, 1,1-diMethylethyl ester 1-Piperidinecarboxylic acid, 4-phenyl-, 1,1-dimethylethyl ester
CAS	123387-49-5
InChI	InChI=1S/C16H23NO2/c1-16(2,3)19-15(18)17-11-9-14(10-12-17)13-7-5-4-6-8-13/h4-8,14H,9-12H2,1-3H3

tert-butyl 4-phenylpiperidine-1-carboxylate - Physico-chemical Properties

Molecular Formula	C16H23NO2
Molar Mass	261.36
Storage Condition	2-8°C
MDL	MFCD09953385

tert-butyl 4-phenylpiperidine-1-carboxylate - Introduction

4-Phenyl-1-piperidinecarboxylic acid tert-butyl ester is an organic compound with the chemical formula C16H21NO2. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: 4-Phenyl-1-piperidinecarboxylic acid tert-butyl ester is a colorless to light yellow liquid.
-Solubility: It has good solubility in common organic solvents.
-Melting point: The melting point of tert-butyl 4-phenyl-1-piperidinecarboxylate is about -30°C.
-Boiling point: Its boiling point range is approximately 220-225°C.
-Stability: tert-butyl 4-phenyl-1-piperidinecarboxylate is relatively stable under regular conditions.

Use:
- 4-phenyl -1-piperidine carboxylic acid tert-butyl ester is commonly used as a reagent in organic synthesis, for example, as a hydrogenation reducing agent, reducing alkyl halide to alkane, epoxidation reagent, etc.
-It can also be used in esterification reactions, acylation reactions, etc. in organic synthesis, as part of a catalyst or solvent.

Preparation Method:
- 4-phenyl -1-piperidine carboxylic acid tert-butyl ester can be obtained by reacting 4-phenyl -1-piperidine methanol with tert-butyl aluminum chloride. The specific step is to react 4-phenyl -1-piperidine methanol with tert-butyl aluminum chloride in an appropriate solvent, and then to obtain the target product after treatment and purification.

Safety Information:
-4-Phenyl-1-piperidinecarboxylic acid tert-butyl ester is irritating and may cause irritation to the eyes, skin and respiratory system.
-Wear appropriate protective equipment such as gloves, goggles and protective masks during use.
-During storage and handling, care should be taken to avoid contact with oxidants and acids to avoid dangerous reactions or safety accidents.
-For the specific safety operation of 4-phenyl-1-piperidinecarboxylic acid tert-butyl ester, please refer to the safety data form of the relevant chemical or consult a professional.

Last Update：2024-04-10 22:29:15